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Efficacy Of IV Morphine vs Remifentanil-Intrathecal Morphine Analgesia During Hepatic Resection Surgery (RITM-IVM)
The patient population requiring hepatic resection can demonstrate an unpredictable risk of exhibiting peri-operative coagulopathy resulting either from the pre-operative hepatic pathophysiology or volume of parenchymal resection. Choice of analgesia can be severely limited. Currently, the most commonly described use of combined remifentanil infusion and intrathecal morphine has been in fast-track cardiac surgery. To date, there are no published data describing its use in the context of major hepatobiliary where the investigators predict it may provide adequate analgesia with a lower rate of adverse effects over the first 24 hours after surgery.
Details
| Lead sponsor | St Vincent's University Hospital, Ireland |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 45 |
| Start date | 2007-09 |
| Completion | 2008-06 |
Conditions
- Liver Dysfunction
- Pain
Interventions
- Morphine sulphate
- Morphine hydrochloride, remifentanil hydrochloride
Primary outcomes
- Opioid-related side effects — First 24 hours post-operatively
Countries
Ireland