Who is sponsoring NCT00552864?

NCT00552864 is sponsored by Centro Cardiologico Monzino.

What condition does NCT00552864 study?

NCT00552864 studies Coronary Artery Bypass, Epidural Anesthesia.

What drugs are being tested in NCT00552864?

Interventions: Ropivacaine, Levobupivacaine.

What is the status of NCT00552864?

NCT00552864 is currently COMPLETED.

Last reviewed 2007-10-31 · How we verify

High Thoracic Epidural Anesthesia and Postoperative Analgesia With Ropivacaine or Levobupivacaine for Coronary Surgery: A Prospective Randomized Double-Blind Comparison

NCT00552864 Phase 4 COMPLETED

In High Thoracic Epidural Anesthesia (HTEA) the use of a local anesthetic (LA) with low cardiac toxicity is crucial as myocardial contractility is often already seriously impaired. The aim of this study is to compare the efficacy, doses and side effects of ropivacaine and levobupivacaine in patients submitted to coronary artery bypass graft with HTEA and general anesthesia. The primary end point is the amount of LA drug required to maintain a VAS \< 4 when coughing in the first 24 postoperative hours.

Details

Lead sponsor	Centro Cardiologico Monzino
Phase	Phase 4
Status	COMPLETED
Enrolment	61
Start date	2003-01
Completion	2005-06

Conditions

Coronary Artery Bypass
Epidural Anesthesia

Interventions

Ropivacaine
Levobupivacaine

Primary outcomes

The amount of local anesthetic drug (mg) required to maintain a visual analog scale score for pain (VAS) < 4 when coughing. — the first 24 postoperative hours

Countries

Italy