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An Eight Week, Double-Blind, Placebo Controlled, Adjunctive Study of the Primary Effects of the Use of Flexible Doses of Modafinil 50mg to 200mg, on the Negative Symptoms, Cognition, and Excessive Daytime Sleepiness in Schizophrenic Patients
The purpose of this study is to test the effect of modafinil on the negative symptoms, such as blunted affect and social withdrawal, of schizophrenic patients and to determine modafinil's effect on excessive daytime sleepiness. A secondary purpose of the study is to examine the effect of modafinil on cognitive functioning of schizophrenic patients.
Details
| Lead sponsor | Veterans Medical Research Foundation |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 26 |
| Start date | 2003-02 |
| Completion | 2008-02 |
Conditions
- Schizophrenia
Interventions
- Modafinil
- Placebo
Primary outcomes
- PANSS, and Sleep/wake activity measured using the Actillume (Ambulatory Monitoring, Inc.) — baseline, one month, two months
Countries
United States