Who is sponsoring NCT00541918?

NCT00541918 is sponsored by Medical University of Gdansk.

What drugs are being tested in NCT00541918?

Interventions in NCT00541918: Diprivan (propofol, Astra Zeneca), Sevorane (sevoflurane, Abbott).

Is NCT00541918 still recruiting?

NCT00541918 is currently withdrawn. Last updated 27 October 2015.

Last reviewed 2015-10-27 · How we verify

NCT00541918

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

COGNITIVE - Comparison of Cognitive Function After Sevoflurane or Propofol Anesthesia for Open-heart Operations

Withdrawn Phase 4 Last updated 27 October 2015

What this trial tests

Phase 4 trial testing Diprivan (propofol, Astra Zeneca) in Other Functional Disturbances Following Cardiac Surgery. Withdrawn.

Timeline

1 June 2007

Primary endpoint
1 April 2015

1 April 2015

Quick facts

Lead sponsor	Medical University of Gdansk
Phase	Phase 4
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	prevention
Start date	1 June 2007
Primary completion	1 April 2015
Estimated completion	1 April 2015
Sites	2 locations across Poland

Drugs / interventions tested

Diprivan (propofol, Astra Zeneca)
Sevorane (sevoflurane, Abbott) — full drug profile →

Conditions studied

Other Functional Disturbances Following Cardiac Surgery — all drugs for Other Functional Disturbances Following Cardiac Surgery →
Memory Disorders — all drugs for Memory Disorders →

Sponsor

Medical University of Gdansk

Who can join

Adults 55 to 80, any sex, with Other Functional Disturbances Following Cardiac Surgery or Memory Disorders. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

results of psychological examination
Time frame: 6 days, 3 and 12 months after surgery

Sponsor's own description

The aim of the study is to prove whether general anesthesia with inhaled sevoflurane reduces the frequency of neurological and cognitive impairment after open-heart operations with use of cardiopulmonary by-pass (CPB) in comparison with intravenous anesthesia with propofol.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other Medical University of Gdansk trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00541918 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of Gdansk
Last refreshed: 27 October 2015

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00541918.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing