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NCT00536068
Platelet Inhibition by Aspirin, Acetaminophen and NSAID
NA trial testing Acetylsalicylic acid, acetaminophen, diclofenac, naproxen, placebo in Hemostasis in 11 participants. Completed in 1 August 2007.
Quick facts
| Lead sponsor | Kantonsspital Graubünden |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 11 |
| Start date | 1 August 2006 |
| Estimated completion | 1 August 2007 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Acetylsalicylic acid, acetaminophen, diclofenac, naproxen, placebo — full drug profile →
Conditions studied
- Hemostasis — all drugs for Hemostasis →
Sponsor
Kantonsspital Graubünden — full company profile →
Who can join
Eligibility, any sex, with Hemostasis. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
platelet aggregation
Time frame: 5 days
Sponsor's own description
Nonsteroidal antiinflammatory drugs such as diclofenac or naproxen may interfere with the inhibition of platelet aggregation by aspirin, because they all interact with the platelet cyclooxygenase.This may be of great clinical importance because of an increased cardiovascular event rate (myocardial infarction, stroke). The present randomized, controlled study analyses in vitro platelet aggregation under a combined treatment of healthy volunteers with aspirin and either acetaminophen, diclofenac, naproxen, or placebo.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00536068
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hemostasis
Currently open trials in the same condition.
- NCT06664788 — A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery · NA · recruiting
- NCT03430609 — Ovarian Function After Use of Various Hemostatic Techniques During Treatment for Endometrioma · NA · active not recruiting
Other Kantonsspital Graubünden trials
Trials by the same sponsor.
- NCT03808155 — Prevention of Postoperative Urinary Retention With Treatment of Tamsulosin 5 Days Prior to Lower Limb Arthroplasty · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00536068 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kantonsspital Graubünden
- Last refreshed: 27 September 2007
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00536068.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing