NCT00520910 is a Phase 2 clinical trial of Polypodium leucotomos in Aging, sponsored by University of Miami.

Who is sponsoring NCT00520910?

NCT00520910 is sponsored by University of Miami.

What drugs are being tested in NCT00520910?

Interventions in NCT00520910: Polypodium leucotomos.

What condition does NCT00520910 study?

NCT00520910 studies Aging, Skin Abnormalities.

Is NCT00520910 still recruiting?

NCT00520910 is currently completed. Last updated 17 June 2019.

Are results published for NCT00520910?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2019-06-17 · How we verify

NCT00520910

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Single-Blind Study Determining the Efficacy of Polypodium Leucotomos Extract Supplement in Decreasing UVA Premutagenic and Photoaging Markers

Completed Phase 2 Results posted Last updated 17 June 2019

What this trial tests

Phase 2 trial testing Polypodium leucotomos in Aging in 10 participants. Completed in 1 May 2009.

Timeline

1 August 2007

Primary endpoint
1 May 2009

1 May 2009

Quick facts

Lead sponsor	University of Miami
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	10
Start date	1 August 2007
Primary completion	1 May 2009
Estimated completion	1 May 2009
Sites	1 location across United States

Drugs / interventions tested

Polypodium leucotomos — full drug profile →

Conditions studied

Aging — all drugs for Aging →
Skin Abnormalities — all drugs for Skin Abnormalities →

Sponsor

University of Miami

Who can join

18 and older, any sex, with Aging or Skin Abnormalities. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Change in Common Deletion (CD) Value in DNA of Skin Biopsy Sample
Time frame: baseline, 24 hours
CD is determined by semiquantitative real-time polymerase chain reaction.
8-oxo-7,8-dihydro-2'-Deoxyguanosine (8-oxo-dG) Quantification in Skin Biopsy Sample Taken From Final Visit
Time frame: 24 hours

Sponsor's own description

With this study, the investigators will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse effects of UVA, a type of ultraviolet light.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Aging

Currently open trials in the same condition.

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NCT07099053 — Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging · recruiting
NCT07504068 — Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in · NA · recruiting
NCT07525453 — Effects of Three Different Exercise Programs on Dynamic Balance in Community-Dwelling Older Adults · NA · recruiting
NCT07500727 — Skeletal Muscle Aging and Responsiveness in Aged People With MS · NA · recruiting

Other University of Miami trials

Trials by the same sponsor.

NCT06003712 — Exploring the Effect of Mindfulness on Quality of Life (QoL) in Spinal Cord Injury (SCI) · NA · not yet recruiting
NCT06077071 — MRIdian "RADAR" Trial · NA · not yet recruiting
NCT07472413 — Alternate Pre-med in Anti-Cluster of Differentiation 20 (CD20) Pilot Project · Phase 3 · not yet recruiting
NCT07322289 — Antibiotic-coated Braided Suture Study · NA · not yet recruiting
NCT07469592 — eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00520910 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Miami
Last refreshed: 17 June 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00520910.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing