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Efficacy of Antihypertensive and Plasma Total Homocysteine Lowering Combined Therapy With Enalapril and Folic Acid in Hypertensive Patients:A Multicenter Double Blind Randomized Clinical Trial
Combinded therapy with folic acid and enalapril may significantly decrease plasma total homocysteine level and had beneficial effect on blood pressure reduction and glycometabolism.
Details
| Lead sponsor | Anhui Medical University |
|---|---|
| Phase | Phase 2 |
| Status | COMPLETED |
| Enrolment | 443 |
| Start date | 2005-09 |
| Completion | 2006-02 |
Conditions
- Plasma Total Homocysteine Level
- Blood Pressure
Interventions
- enalapril plus folic acid
Primary outcomes
- Blood pressure of study participants was measured at baseline, 2th week, 4th week, 6th week and at the end of trial Subjects' plasma total homocysteine concentration were measured at baseline, 4th week and at 8th week. — 8 weeks
Countries
China