Who is sponsoring NCT00514150?

NCT00514150 is sponsored by Tehran University of Medical Sciences.

What condition does NCT00514150 study?

NCT00514150 studies Contrast Induced Nephropathy.

What drugs are being tested in NCT00514150?

Interventions: Sodium Bicarbonate plus normal saline 0.9%, normal saline 0.9%.

What is the status of NCT00514150?

NCT00514150 is currently COMPLETED.

Last reviewed 2008-09-04 · How we verify

Comparing Sodium Bicarbonate Plus Isotonic Normal Saline Versus Isotonic Normal Saline Alone to Prevent Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography: A Randomized Controlled Trial

NCT00514150 Phase 3 COMPLETED

Radio Contrast Induced Nephropathy (RCIN) remains a well recognized complication in patients undergoing diagnostic or interventional procedures requiring radiographic contrast agents. Recent studies have shown benefit in administering Sodium Bicarbonate over normal saline( the uniformly accepted prophylaxy) in preventing RCIN.Therefore the aim of the study is to evaluate the efficacy of sodium bicarbonate solved in normal saline compared with infusion of normal saline in prevention of RCIN.

Details

Lead sponsor	Tehran University of Medical Sciences
Phase	Phase 3
Status	COMPLETED
Enrolment	265
Start date	2007-08
Completion	2008-06

Conditions

Contrast Induced Nephropathy

Interventions

Sodium Bicarbonate plus normal saline 0.9%
normal saline 0.9%

Primary outcomes

development of contrast induced nephropathy defined as an absolute (> or = 0.5 mg/dl) or relative increase (> or = 25%) in serum creatinine at 48 hours after exposure to a contrast agent compared to baseline serum creatinine values. — at 48 hours

Countries

Iran