Multicenter Randomized Phase II Study of Methotrexate (MTX) and Temozolomide Versus MTX, Procarbazine, Vincristine and Cytarabine for Primary CNS Lymphoma (PCNSL) in the Elderly (CNSLymphoma)

NCT00503594 Phase 2 UNKNOWN

The purpose of this study is to evaluate two types of chemotherapy for primary central nervous system lymphoma in the elderly (age older than 60) : * Methotrexate, procarbazine, vincristine and cytarabine * Methotrexate and temozolomide

Details

Lead sponsor	Assistance Publique - Hôpitaux de Paris
Phase	Phase 2
Status	UNKNOWN
Enrolment	92
Start date	2007-07
Completion	2012-07

Conditions

• Lymphoma

Interventions

• Methotrexate and temozolomide
• Methotrexate , procarbazine ,vincristine ,cytarabine

Primary outcomes

• Progression-free survival — at one year

Countries

France