Local Application of Collagen-Gentamicin in Addition to Fixation of the Sternum With Extra Sternal Wires for Prevention of Sternal Wound Infection in Cardiac Surgery (LOGIX)

NCT00484055 NA COMPLETED

The aim of the present study is to evaluate a new technique for prevention of sternal wound infection consisting of local application of collagen-gentamicin in addition to routine i.v. antibiotic prophylaxis. The technique has been evaluated in a previous randomised study. The aim of the present study is to evaluate the technique after it has been introduced in clinical practise to monitor the bacterial antibiotic susceptibility and to verify that the suggested reduction in sternal wound infection still exits.

Details

Lead sponsor	Region Örebro County
Phase	NA
Status	COMPLETED
Enrolment	1358
Start date	2007-01
Completion	2008-08

Conditions

• Drug Resistance, Bacterial
• Postoperative Wound Infection

Interventions

• Local application of collagen-gentamicin
• Fixation of the sternotomy with more than six wires

Primary outcomes

• The incidences of methicillin- and gentamicin resistant microbiological agents in sternal wound infections that develop in study patients — Within 2 months postoperatively

Countries

Sweden