A Prospective, Multicenter, Open-Label, Randomized, Comparative Study to Evaluate the Efficacy, Safety, and Tolerability of Ertapenem Versus Ceftriaxone/Metronidazole in the Treatment of Intra-Abdominal Infections in Adults

NCT00481702 Phase 3 COMPLETED

A multicenter study to evaluate the effectiveness of ertapenem compared to ceftriaxone/metronidazole in treating certain abdominal infections that require surgery in adult patients.

Details

Lead sponsor	Merck Sharp & Dohme LLC
Phase	Phase 3
Status	COMPLETED
Enrolment	300
Start date	2001-12
Completion	2003-06

Conditions

• Intra-abdominal Infection

Interventions

• Comparator: ceftriaxone sodium / Duration of Treatment: 8 Weeks
• MK0826, /Duration of Treatment : 8 Weeks
• Comparator: metronidazole / Duration of Treatment: 8 Weeks

Primary outcomes

• That ertapenem is as effective as ceftriaxone/metronidazole in the treatment of an abdominal infection — 2 weeks after treatment