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NCT00479206
Artemisinin Resistance in Cambodia
NA trial testing Artesunate in Malaria, Falciparum. Completed in 1 February 2007.
Quick facts
| Lead sponsor | Medical University of Vienna |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Start date | 1 October 2006 |
| Estimated completion | 1 February 2007 |
| Sites | 1 location across Cambodia |
Drugs / interventions tested
- Artesunate (ARTESUNATE) — full drug profile →
Conditions studied
- Malaria, Falciparum — all drugs for Malaria, Falciparum →
Sponsor
Medical University of Vienna
Who can join
Adults 18 to 65, any sex, with Malaria, Falciparum. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
- Primary clinical outcome is cure (Adequate Clinical and Parasitological Response - ACPR as defined by WHO criteria) on Day 28.
Sponsor's own description
The principal aim of this project is to investigate reports of developing artemisinin resistance in Cambodia using an integrated in vivo - in vitro approach to examine recent alarming reports of treatment failures with advanced combination therapies along the Thai-Cambodian border, which could have major impact on the malaria situation in the affected areas as well as the rest of the malaria-endemic world.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia.
Noedl H, Se Y, Sriwichai S, Schaecher K, et al · · 2010 · cited 140× · PMID 21028985 · DOI 10.1086/657120
Verify or expand the search:
- PubMed search for NCT00479206
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT07095478 — Safety and Efficacy of Oral Artesunate for Pre-cervical Cancer · Phase 2 · not yet recruiting
- NCT06853184 — Study Evaluating the Efficacy and Safety of Artesunate · Phase 2 · recruiting
- NCT06294912 — A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003) · Phase 1 · completed
Other recruiting trials for Malaria, Falciparum
Currently open trials in the same condition.
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00479206 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of Vienna
- Last refreshed: 29 April 2008
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00479206.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing