Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)

NCT00473694 PHASE3 COMPLETED Results posted

The purpose of the trial is to demonstrate a faster recovery from neuromuscular block (NMB) induced with rocuronium or vecuronium after reversal by 4.0 mg/kg of Org 25969 compared with reversal by 70 μg/kg of neostigmine in combination with 14 μg/kg glycopyrrolate.

Details

Lead sponsor	Merck Sharp & Dohme LLC
Phase	PHASE3
Status	COMPLETED
Enrolment	182
Start date	Mon Nov 28 2005 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Jan 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Anesthesia, General

Interventions

• sugammadex
• neostigmine
• vecuronium
• rocuronium
• glycopyrrolate