Last reviewed · How we verify
An Open-label, Randomized, Parallel Group Study Comparing the Efficacy and Safety of Amlodipine in Combination With Valsartan Compared to Losartan in Combination With Hydrochlorothiazide Given for 52 Weeks on the Regression of Left Ventricular Hypertrophy in Patients With Mild to Moderate Hypertension
This study will evaluate the safety and efficacy of amlodipine plus valsartan in patients with hypertension and left ventricular hypertrophy
Details
| Lead sponsor | Novartis |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 90 |
| Start date | 2007-03 |
| Completion | 2010-03 |
Conditions
- Hypertension; Hypertrophy, Left Ventricular
Interventions
- Valsartan
- Amlodipine
- Hydrochlorothiazide
- Losartan
Primary outcomes
- Change From Baseline in Left Ventricular Mass Index (LVMI) Measured Via Magnetic Resonance Imaging (MRI) — Baseline to week 52
Countries
Germany