A Randomized Trial to Assess the Utility of Empirical Anti-Arrhythmic Drug Therapy to Prevent Atrial Arrhythmia During the 6 Weeks Following Pulmonary Vein Isolation to Treat Paroxysmal Atrial Fibrillation

NCT00408200 NA COMPLETED Results posted

The purpose of this study is to examine the overall effectiveness of anti-arrhythmic medicines (to control heart rhythm) prescribed after an ablation procedure for atrial fibrillation.

Details

Lead sponsor	University of Pennsylvania
Phase	NA
Status	COMPLETED
Enrolment	110
Start date	2006-11
Completion	2008-06

Conditions

• Atrial Fibrillation

Interventions

• propafenone; flecainide; sotalol; dofetilide
• Radiofrequency catheter ablation

Primary outcomes

• Composite Endpoint: Atrial Arrhythmias Lasting >24 Hrs or Requiring Antiarrhythmic Drug Therapy; Need for Cardioversion/Repeat Ablation During the Study Period; Adverse Outcome/Intolerance of Antiarrhythmic Agent Requiring Cessation or Change of Drug — 6 weeks

Countries

United States