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NCT00404638
Treatment of Enuresis Nocturna by Circular Muscle Exercise (Paula Method)
NA trial testing Desmopresin in Monosymptomatic Enuresis Nocturna in 40 participants. Status unknown.
Quick facts
| Lead sponsor | Rabin Medical Center |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 December 2006 |
| Sites | 2 locations across Israel |
Drugs / interventions tested
- Desmopresin — full drug profile →
- Paula Method of Circular Muscle Exercise
Conditions studied
- Monosymptomatic Enuresis Nocturna — all drugs for Monosymptomatic Enuresis Nocturna →
Sponsor
Rabin Medical Center
Who can join
Adults 5 to 15, any sex, with Monosymptomatic Enuresis Nocturna. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Several treatment modalities for children suffering from monosymptomathic nocturnal enuresis are available including drugs, alarms, acupuncture, pelvic floor training and biofeedback. The aim of this study is to to test if Paula Method (circular muscle exercise) can be an another treatment modality.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Alarm interventions for nocturnal enuresis in children.
Caldwell PH, Codarini M, Stewart F, Hahn D, et al · · 2020 · cited 15× · PMID 32364251 · DOI 10.1002/14651858.cd002911.pub3 -
Physical activity for lower urinary tract symptoms secondary to benign prostatic obstruction.
Silva V, Grande AJ, Peccin MS. · · 2019 · cited 14× · PMID 30953341 · DOI 10.1002/14651858.cd012044.pub2
Verify or expand the search:
- PubMed search for NCT00404638
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00404638 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rabin Medical Center
- Last refreshed: 28 November 2006
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00404638.
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