An Open-label, Single-center Study of the Effects of Co-artemether, Atovaquone-proguanil, and Artesunate-mefloquine on Auditory Function Following the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria in Patients 12 Years of Age or Older.

NCT00386750 Phase 4 TERMINATED

THIS STUDY IS NOT ENROLLING PATIENTS IN THE USA. To evaluate the effects of artemether/ lumefantrine on the auditory function.

Details

Lead sponsor	Novartis Pharmaceuticals
Phase	Phase 4
Status	TERMINATED
Enrolment	265
Start date	2005-06
Completion	2005-11

Conditions

• Malaria
• Falciparum

Interventions

• Artemether-lumefantrine

Primary outcomes

• Auditory abnormalities at Day 7 assessed by Auditory Brainstem Response (ABR) wave form latencies (a type of hearing test).