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Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT) (LDOT)
The purpose of this study was to determine whether a low dose an opiate pain medication is effective for the treatment of discomfort in patients with advanced dementia. The study medication was also known as Lortab and contained both a narcotic pain medication and acetaminophen (the same pain medication as contained in Tylenol). This study was an eight-week long clinical trial for discomfort among veterans with advanced dementia who were admitted to a Nursing Home Care Unit (NHCU) at the Tuscaloosa VA Medical Center.
Details
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 11 |
| Start date | 2007-10 |
| Completion | 2014-06 |
Conditions
- Alzheimer Disease
- Dementia
- Dementia, Vascular
- Pain
Interventions
- hydrocodone/APAP w placebo PRN
- hydrocodone/APAP
- placebo with hydrocodone/APAP PRN
Primary outcomes
- Pain Assessment in Advanced Dementia (PAINAD) — Two (2) weeks
Pain intensity observational assessment for persons with severe dementia. Higher scores indicate more pain/discomfort. Scale range is 0-10.
Countries
United States