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Prevalence of Salivary Hypofunction in Patients With Globus Pharyngeus

NCT00381771 COMPLETED

It is well known that 'globus sensation in throat' is caused by the chronic irritation and inflammation of oral, pharyngeal, or laryngeal mucosa, such as laryngopharyngeal reflux and chronic postnasal drip. Xerostomia and pharyngoxerosis due to salivary hypofunction also proved to induce the mucosal change of the oral cavity and pharynx. However, no previous studies have documented the prevalence of salivary hypofunction in patients with globus pharyngeus. Through this clinical investigation, we hypothesized that the salivary hypofunction might be one of the leading cause of globus pharyngeus.

Details

Lead sponsorSamsung Medical Center
StatusCOMPLETED
Enrolment340
Start date2006-02
Completion2007-12

Conditions

Interventions

Countries

South Korea