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NCT00373061: EXPECT
An Observational Study of the Use and Safety of Xolair® During Pregnancy
trial testing Xolair® in Asthma in 309 participants. Completed in 5 January 2018.
11 December 2017
Quick facts
| Lead sponsor | Genentech, Inc. |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 309 |
| Start date | 20 October 2006 |
| Primary completion | 11 December 2017 |
| Estimated completion | 5 January 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Xolair®
Conditions studied
- Asthma — all drugs for Asthma →
Sponsor
Genentech, Inc. — full company profile →
Who can join
Eligibility, female only, with Asthma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Xolair® Pregnancy Registry is an observational study established by Genentech to obtain data on pregnancy outcomes in women who are exposed to Xolair®. Women exposed to at least one dose of Xolair® within 8 weeks prior to conception or at any time during their pregnancy will be followed to completion of their pregnancies. The evaluation of infants will be conducted at birth and at 6-month intervals until the infants are 12 months old. Follow-up of the infant will be extended until the infant is 18 months old, if the woman continues Xolair® treatment while breastfeeding.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Pediatric asthma: An unmet need for more effective, focused treatments.
Papadopoulos NG, Čustović A, Cabana MD, Dell SD, et al · · 2019 · cited 51× · PMID 30312503 · DOI 10.1111/pai.12990
Verify or expand the search:
- PubMed search for NCT00373061
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00373061 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Genentech, Inc.
- Last refreshed: 14 February 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00373061.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing