Who is sponsoring NCT00362245?

NCT00362245 is sponsored by Rambam Health Care Campus.

What condition does NCT00362245 study?

NCT00362245 studies Gram Negative Meningitis, Post Traumatic Bacterial Meningitis.

What drugs are being tested in NCT00362245?

Interventions: Systemic and Intra-Thecal Amikacin Therapy.

What is the status of NCT00362245?

NCT00362245 is currently WITHDRAWN.

Last reviewed 2015-11-01 · How we verify

Amikacin Penetration Into the Cerebrospinal Fluid: Pharmacokinetic/Pharmacodynamic Analysis in Adults With Hospital Acquired Gram-negative Meningitis Associated With Intracranial Pressure Monitoring and Draining Devices

NCT00362245 Phase 4 WITHDRAWN

The limited available data precludes establishing an antibiotic regimen in patients suffering from bacterial meningitis after head trauma, or spontaneous bleeding Understanding the disposition of Amikacin administered intrathecally will enable to propose rational treatment of these patients.

Details

Lead sponsor	Rambam Health Care Campus
Phase	Phase 4
Status	WITHDRAWN
Start date	2006-09
Completion	2008-11

Conditions

Gram Negative Meningitis
Post Traumatic Bacterial Meningitis

Interventions

Systemic and Intra-Thecal Amikacin Therapy

Primary outcomes

Bactericidal effect on the causative bacteria
Blood and CSF AUC/MIC relationship

Countries

Israel