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NCT00357513

Genetic Studies to Identify Stroke Subtypes and Outcome

Completed Last updated 2 July 2017
What this trial tests

trial in Cerebrovascular Disease in 840 participants. Completed in 15 December 2008.

Timeline
3 June 2002
15 December 2008

Quick facts

Lead sponsorNational Institute of Neurological Disorders and Stroke (NINDS)
StatusCompleted
Study typeOBSERVATIONAL
Enrollment840
Start date3 June 2002
Estimated completion15 December 2008
Sites3 locations across United States

Conditions studied

Sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Who can join

21 and older, any sex, with Cerebrovascular Disease or Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will characterize the gene response of the body's immune and inflammatory cells to stroke. There is a wide variation in stroke risk, stroke outcome, and response to clot-busting therapy for stroke. This variation may be due to differences in people's response to injury or infection, or to differences in genetic make-up between individuals. Genes store the biological information that determines the body's response to injury or infection. This study will analyze the activity of a large number of genes to try to learn which genes might be related to patient outcome. This, in turn, may lead to an understanding of which gene profiles are related to increased stroke risk and increased disability or death. Healthy volunteers over age 21 and stroke patients over age 21 who are admitted to the NIH Stroke Program at Suburban Hospital in Bethesda, Md., may be eligible for this study. Volunteers will be screened with a medical history, blood pressure and pulse measurements, electrocardiogram, and neurological examination. Participants will have 20 to 35 milliliters (about an ounce) of blood drawn for genetic studies. The genetic material will be extracted from the white blood cells and analyzed for normal and abnormal gene activity related to stroke. ...

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Cerebrovascular Disease

Currently open trials in the same condition.

Other National Institute of Neurological Disorders and Stroke (NINDS) trials

Trials by the same sponsor.

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing