NCT00355667 (J-MELODIC) is a Phase 4 clinical trial of furosemide in Congestive Heart Failure, sponsored by Hyogo Medical University.

Who is sponsoring NCT00355667?

NCT00355667 is sponsored by Hyogo Medical University.

What drugs are being tested in NCT00355667?

Interventions in NCT00355667: furosemide, azosemide.

What condition does NCT00355667 study?

NCT00355667 studies Congestive Heart Failure.

Is NCT00355667 still recruiting?

NCT00355667 is currently completed. Last updated 17 August 2016.

Last reviewed 2016-08-17 · How we verify

NCT00355667: J-MELODIC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Japanese Multicenter Evaluation of Long- Versus Short-acting Diuretics in Congestive Heart Failure

Completed Phase 4 Last updated 17 August 2016

What this trial tests

Phase 4 trial testing furosemide in Congestive Heart Failure in 320 participants. Completed in 1 August 2010.

Timeline

1 June 2006

Primary endpoint
1 August 2010

1 August 2010

Quick facts

Lead sponsor	Hyogo Medical University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	320
Start date	1 June 2006
Primary completion	1 August 2010
Estimated completion	1 August 2010
Sites	1 location across Japan

Drugs / interventions tested

furosemide (furosemide) — full drug profile →
azosemide (AZOSEMIDE) — full drug profile →

Conditions studied

Congestive Heart Failure — all drugs for Congestive Heart Failure →

Sponsor

Hyogo Medical University

Who can join

20 and older, any sex, with Congestive Heart Failure. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

a composite of cardiovascular death and unplanned admission to hospital for congestive heart failure
Time frame: 2 years

Sponsor's own description

The purpose of this study is to compare therapeutic effects of furosemide, a short-acting loop diuretic, and azosemide, a long-acting one, in patients with heart failure, and to test our hypothesis that long-acting diuretics are superior to short-acting types in heart failure.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of furosemide

Trials testing the same drug.

NCT04343235 — Postpartum Management of Gestational Hypertensive Disorders Using Furosemide · Phase 4 · terminated
NCT02960412 — Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy · Phase 4 · completed

Other recruiting trials for Congestive Heart Failure

Currently open trials in the same condition.

NCT07008365 — The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure · Phase 3 · recruiting
NCT06526884 — Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC) · NA · active not recruiting
NCT06495892 — PVP-Guided Decongestive Therapy in HF 2 · Phase 4 · recruiting
NCT06374277 — Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence · NA · recruiting
NCT05971225 — Verifying Remote Monitoring Effect on Net Cardiovascular Outcome; RemoteVerify (RêVe) · NA · recruiting

Other Hyogo Medical University trials

Trials by the same sponsor.

NCT07347665 — Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the M2 Segment of Middle C · NA · recruiting
NCT06318286 — Study of Pembrolizumab Plus Chemotherapy With Lenvatinib for Malignant Pleural Mesothelioma · Phase 2 · recruiting
NCT03702413 — Randomized Controlled Trial of Endovascular Therapy for Acute Large Vessel Occlusion With Large Ischemic Core · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00355667 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hyogo Medical University
Last refreshed: 17 August 2016

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00355667.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing