NCT00354198 is a Phase 3 clinical trial of pentoxifylline in Glomerulonephritis, sponsored by National Taiwan University Hospital.

Who is sponsoring NCT00354198?

NCT00354198 is sponsored by National Taiwan University Hospital.

What drugs are being tested in NCT00354198?

Interventions in NCT00354198: pentoxifylline, corticosteroids.

What condition does NCT00354198 study?

NCT00354198 studies Glomerulonephritis.

Is NCT00354198 still recruiting?

NCT00354198 is currently terminated. Last updated 12 November 2012.

Last reviewed 2012-11-12 · How we verify

NCT00354198

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Efficacy of Combined Pentoxifylline and Conventional Immunosuppressive Regimens on Patients With Rapidly Progressive Glomerulonephritis

Terminated Phase 3 Last updated 12 November 2012

What this trial tests

Phase 3 trial testing pentoxifylline in Glomerulonephritis in 7 participants. Terminated before completion.

Timeline

1 August 2006

Primary endpoint
1 August 2009

1 June 2010

Quick facts

Lead sponsor	National Taiwan University Hospital
Phase	Phase 3
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	7
Start date	1 August 2006
Primary completion	1 August 2009
Estimated completion	1 June 2010
Sites	1 location across Taiwan

Drugs / interventions tested

pentoxifylline — full drug profile →
corticosteroids (corticosteroids) — full drug profile →

Conditions studied

Glomerulonephritis — all drugs for Glomerulonephritis →

Sponsor

National Taiwan University Hospital

Who can join

Adults 20 to 80, any sex, with Glomerulonephritis. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

initiation of acute dialysis or doubling of serum creatinine levels
Time frame: 3 months

Sponsor's own description

We have recently demonstrated that pentoxifylline (PTX) has the potential to treat severe glomerular inflammation in a rat model of accelerated anti-glomerular basement membrane (GBM) glomerulonephritis. This study aims to investigate the therapeutic effects of combined PTX and conventional immunosuppressive regimens on patients with rapidly progressive glomerulonephritis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of pentoxifylline

Trials testing the same drug.

NCT05971667 — Effect of Tadalafil, Sildenafil and Pentoxyfylline on Frozen Embryo Transfer Outcomes · Phase 2, PHASE3 · unknown
NCT03476564 — Effects of Pentoxifylline and Vitamin E on Pregnancy Rate in Infertile Women Treated by ICSI: · EARLY_PHASE1 · unknown
NCT03664414 — Pentoxifylline Effect in Patients With Diabetic Nephropathy.(PENFOSIDINE STUDY) · Phase 4 · unknown

Other recruiting trials for Glomerulonephritis

Currently open trials in the same condition.

NCT06858319 — Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. · Phase 3 · recruiting
NCT06835322 — Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis · Phase 2 · recruiting
NCT04662723 — Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy. · Phase 4 · recruiting
NCT05434325 — TESTING -ON Post-Trial ObservatioNal Cohort Study · recruiting
NCT04663204 — A Study of the Safety and Activity of Sparsentan for the Treatment of Incident Patients With Immunoglobulin A Nephropath · Phase 2 · active not recruiting

Other National Taiwan University Hospital trials

Trials by the same sponsor.

NCT06936917 — Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest · not yet recruiting
NCT05396222 — A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar · NA · not yet recruiting
NCT07532356 — Integrating Tumor Genomics and Urinary Exosomal Proteomics to Establish a Multi-Layer Biomarker Framework for Early Risk · not yet recruiting
NCT07317310 — The NTU JO-SMART Study · NA · not yet recruiting
NCT07382024 — Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00354198 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
Last refreshed: 12 November 2012

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00354198.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing