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NCT00342329

Lupus Nephritis: Role of Environmental and Occupational Exposures

Completed Last updated 2 July 2017
What this trial tests

trial in Lupus Nephritis. Completed in 7 March 2007.

Timeline
16 April 2001
7 March 2007

Quick facts

Lead sponsorNational Institute of Environmental Health Sciences (NIEHS)
StatusCompleted
Study typeOBSERVATIONAL
Start date16 April 2001
Estimated completion7 March 2007
Sites2 locations across United States

Conditions studied

Sponsor

National Institute of Environmental Health Sciences (NIEHS)

Who can join

Eligibility, any sex, with Lupus Nephritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to examine hormonal and environmental risk factors (and possible gene-environmental interactions) involved in the etiology of lupus nephritis. Our study will focus on exposures to occupational and environmental agents that have been linked to the development of systemic lupus erythematosus (SLE) or renal disease (e.g., silica dust, smoking). We will also assess potential gene environment interactions. We will examine these exposures in 100 patients with renal biopsy with documented proliferative or membraneous nephritis. We will compare exposures in the lupus nephritis patients to lupus patients who do not have nephritis and to normal controls who have participated in the Carolina Lupus Study. One hundred lupus nephritis patients (age 18 years or older, of both genders and all races) will be identified through the Glomerular Disease Collaborative Network (GDCN) Nephropathology database and participating nephrologists at the Medical University of South Carolina, Duke University Medical Center and the East Carolina Medical School.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Lupus Nephritis

Currently open trials in the same condition.

Other National Institute of Environmental Health Sciences (NIEHS) trials

Trials by the same sponsor.

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Data sources for this page

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