NCT00342082 is a clinical trial in Cord Blood, sponsored by National Institute of Environmental Health Sciences (NIEHS).

Who is sponsoring NCT00342082?

NCT00342082 is sponsored by National Institute of Environmental Health Sciences (NIEHS).

What condition does NCT00342082 study?

NCT00342082 studies Cord Blood.

Is NCT00342082 still recruiting?

NCT00342082 is currently completed. Last updated 2 July 2017.

Last reviewed 2017-07-02 · How we verify

NCT00342082

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Anti-HIV Therapy on Red Blood Cells of HIV-infected Mothers and Their Infants

Completed Last updated 2 July 2017

What this trial tests

trial in Cord Blood. Completed in 28 December 2007.

Timeline

25 June 2004

28 December 2007

Quick facts

Lead sponsor	National Institute of Environmental Health Sciences (NIEHS)
Status	Completed
Study type	OBSERVATIONAL
Start date	25 June 2004
Estimated completion	28 December 2007
Sites	3 locations across United States

Conditions studied

Cord Blood — all drugs for Cord Blood →

Sponsor

National Institute of Environmental Health Sciences (NIEHS)

Who can join

Eligibility, any sex, with Cord Blood. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This collaborative investigation between NIEHS, Duke University, and the University of North Carolina (UNC) will study red blood cells of babies born to HIV-infected women receiving anti-retroviral treatment. Studies have shown that newborn mice whose mothers were given anti-HIV medications during pregnancy had abnormal red blood cells circulating in their blood stream, indicating genetic damage to the cells caused by the anti-HIV medications. It is not known if similar red blood cell abnormalities develop in human infants whose mothers received anti-HIV medication during their pregnancy. This study will examine red blood cells from infants exposed to anti-HIV medications and from non-exposed infants to look for differences between them involving this specific genetic damage. Healthy pregnant women and HIV-infected pregnant women who received antiretroviral treatment during their last trimester of pregnancy and during labor may be eligible for this study. Babies of HIV-infected women are also included in the study. Candidates will be recruited from medical centers at Duke University and the UNC. HIV-infected mothers must plan to have their baby followed by either the UNC or the Duke Pediatric Infectious Disease clinic. All women in the study will have 1 milliliter (less than 1/2 teaspoon) of blood collected for this study during delivery at the same time that other blood samples are obtained for their medical care. In addition, 5 ml (1 teaspoon) of umbilical cord blood will also be collected for this study at the time of delivery after the cord is no longer attached to the baby. This concludes participation of non-HIV infected women. Babies born to HIV-infected mothers will have 1 ml of blood drawn between 0 to 3 days of life, between 4 to 6 weeks of life, and between 4 to 6 months of life. These bloodsamples will be collected at the same time as other routine scheduled blood draws.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Cord Blood

Currently open trials in the same condition.

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NCT06381817 — Haplo-cord HCT vs. Haplo-HCT for T-ALL Patients · Phase 3 · recruiting

Other National Institute of Environmental Health Sciences (NIEHS) trials

Trials by the same sponsor.

NCT07111065 — FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM) · Phase 2 · recruiting
NCT06991751 — A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of C · not yet recruiting
NCT07437976 — A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity · not yet recruiting
NCT06325696 — H01 in Adults With Interstitial Lung Disease (The SOLIS Study) · Phase 2 · recruiting
NCT05666739 — NIEHS Repository of Stored Biological Samples for Future Use · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00342082 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Institute of Environmental Health Sciences (NIEHS)
Last refreshed: 2 July 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00342082.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing