NCT00341445

Cockroach Allergen Reduction by Extermination Alone in Low-Income, Urban Homes: A Randomized Control Trial

Completed Phase 1 Last updated 5 April 2018

What this trial tests

Phase 1 trial testing Effect of Cockroach Allergen in Allergens in 64 participants. Completed in 12 February 2007.

Timeline

12 August 2004

Primary endpoint
12 February 2007

12 February 2007

Quick facts

Lead sponsor	National Institute of Environmental Health Sciences (NIEHS)
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	64
Start date	12 August 2004
Primary completion	12 February 2007
Estimated completion	12 February 2007
Sites	1 location across United States

Drugs / interventions tested

• Effect of Cockroach Allergen

Conditions studied

• Allergens — all drugs for Allergens →

Sponsor

National Institute of Environmental Health Sciences (NIEHS)

Who can join

21 and older, any sex, with Allergens. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The most important risk factor for asthma in inner-city homes may be exposure to cockroach allergen. In a previous study, the researchers reported that extermination alone, without resident education or professional cleaning, reduced allergen levels in inner-city homes. This result contradicted earlier findings by other scientists. This study seeks to confirm the researchers' earlier results, and to determine how intensive an effective extermination must be.

The study will last one year and include 60 infested, multi-unit rental homes in North Carolina, divided into three groups. In the Treatment-1 group, researchers from North Carolina State University will set insecticide bait in initial and follow-up visits, as the highest standard for treatment. In the Treatment-2 group, one of five commercial pest-control companies will be randomly assigned to treat each home according to a 12-month, pre-paid contract. The third group will be a control group that receives no extermination treatment. In all homes, researchers will periodically survey the residents, monitor cockroach numbers, and monitor allergen levels in dust samples. If this study is successful, it will be used to plan future asthma prevention trials.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.