A Phase I Study of ZD1839 (Iressa) and Hypofractionated Thoracic Radiotherapy With Stereotactic Body Frame Immobilization for Patients With Advanced Non-Small Cell Lung Cancer

NCT00328562 Phase 1 COMPLETED Results posted

The purpose of this study is to determine the safety and effectiveness of Iressa when used with a short course of high dose radiation therapy in patients with lung cancer.

Details

Lead sponsor	Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Phase	Phase 1
Status	COMPLETED
Enrolment	13
Start date	2003-12
Completion	2010-09

Conditions

• Non-Small Cell Lung Carcinoma (NSCLC)

Interventions

• ZD1839 (Iressa)
• Thoracic Radiotherapy

Primary outcomes

• Patients Affected by Treatment-related Morbidities — Twice weekly during RT and at 1-, 2-, 3-, 4-, 5-, and 6-month points after therapy
  See "Adverse Events" section for specific toxicities

Countries

United States