Last reviewed · How we verify
NCT00311870
Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathy
Phase 4 trial testing nisoldipine in Diabetic Nephropathy in 52 participants. Completed in 1 April 1999.
Quick facts
| Lead sponsor | Steno Diabetes Center Copenhagen |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 1 March 1993 |
| Estimated completion | 1 April 1999 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- nisoldipine (NISOLDIPINE) — full drug profile →
- lisinopril (lisinopril) — full drug profile →
Conditions studied
- Diabetic Nephropathy — all drugs for Diabetic Nephropathy →
Sponsor
Steno Diabetes Center Copenhagen — full company profile →
Who can join
Adults 18 to 55, any sex, with Diabetic Nephropathy. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
- change in glomerular filtration rate from study start to study end
Sponsor's own description
The aim of the study was to compare the renoprotective effect of a long acting calcium antagonist (nisoldipine) with an angiotensin converting enzyme inhibitor (lisinopril)in type 1 diabetic patients with diabetic kidney disease. In total, 51 patients were randomised to treatment with one of these drugs for 4 years. Changes in kidney function, blood pressure and urinary excretion of albumin were measured every 6 months
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00311870
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Diabetic Nephropathy
Currently open trials in the same condition.
- NCT06661174 — A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy · recruiting
- NCT00342927 — Family Investigation of Nephropathy and Diabetes (F.I.N.D.) · recruiting
Other Steno Diabetes Center Copenhagen trials
Trials by the same sponsor.
- NCT07485075 — Digital Support for Reducing Salt Intake Among Patients With Diabetic Kidney Disease: Protocol for a Controlled Clinical · NA · recruiting
- NCT07427251 — The Postprandial Hypo-Avoid Study · Phase 4 · not yet recruiting
- NCT06954090 — Urinary Proteomics to Guide Early Intervention to Prevent Complications in Type 2 Diabetes - a Feasibility Study · Phase 4 · enrolling by invitation
- NCT06832059 — Precision Nutrition Versus Standard Dietary Care: Continuous Glucose Monitoring as a Tool for Guided Nutrition Care in T · NA · recruiting
- NCT07377266 — The Impact of Changing to a New Child- and Family-centered Outpatient Diabetes Clinic Focusing on Early Involvement of t · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00311870 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Steno Diabetes Center Copenhagen
- Last refreshed: 4 April 2006
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00311870.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing