Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies Combining Steroids With or Without Immunosuppressants (CORTAGE)

NCT00307671 Phase 4 COMPLETED

The aim of this trial is to lower the morbidity rate in elderly patients affected with systemic necrotizing vasculitides, by reducing mortality and improving global outcome.

Details

Lead sponsor	Assistance Publique - Hôpitaux de Paris
Phase	Phase 4
Status	COMPLETED
Enrolment	108
Start date	2005-07
Completion	2011-07

Conditions

• Vasculitis
• Wegener's Granulomatosis
• Microscopic Polyangiitis
• Churg-Strauss Syndrome
• Polyarteritis Nodosa

Interventions

• prednisone, methylprednisolone,cyclophosphamides
• Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
• Mycophenolate mofetil,methotrexate

Primary outcomes

• Number of side effects (morbidity) — at 3 years

Countries

France