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Nicotine and Smoking Cessation in Schizophrenia
Many individuals with schizophrenia smoke cigarettes. Individuals in the schizophrenic population often find it difficult to quit smoking. The purpose of this trial is to determine the safety and effectiveness of bupropion in treating individuals with schizophrenia who smoke.
Details
| Lead sponsor | National Institute on Drug Abuse (NIDA) |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 51 |
| Start date | 1998-08 |
| Completion | 2004-02 |
Conditions
- Tobacco-Use Disorder
- Schizophrenia
- Psychotic Disorders
Interventions
- bupropion SR
- Cognitive Behavioral Group Therapy
- nicotine replacement therapy
Primary outcomes
- seven-day point prevalence of smoking reduction, defined as 50 % reduction in serum cotinine levels compared to baseline — end of treatment
Countries
United States