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NCT00292695
A Phase II Study of Concurrent Chemoradiation for The Localized Nasal NK/T-cell Lymphoma
Phase 2 trial testing VP-16, Cisplatin, Ifosfamide, Dexamethosone, Mesna, IF-RT in Lymphoma in 33 participants. Completed in 1 December 2010.
1 December 2009
Quick facts
| Lead sponsor | National Health Research Institutes, Taiwan |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 33 |
| Start date | 1 May 2006 |
| Primary completion | 1 December 2009 |
| Estimated completion | 1 December 2010 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- VP-16, Cisplatin, Ifosfamide, Dexamethosone, Mesna, IF-RT
Conditions studied
- Lymphoma — all drugs for Lymphoma →
Sponsor
National Health Research Institutes, Taiwan
Who can join
Under 70, any sex, with Lymphoma. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
tumor response by CT scan or MRI
Time frame: the first course of DVIP, one month after the last course of DVIP
Sponsor's own description
To determine whether adding combinational chemotherapy concurrently to conventional radiation will improve the response rate, event-free survival, and overall survival. To test the dose intensity and toxicity of chemotherapy in concurrence with radiation. To detect the blood EBV DNA level in Chinese Nasal NK/T-cell lymphoma patients and correlate to the treatment response and prognosis.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Long-term results of a phase II trial with frontline concurrent chemoradiotherapy followed by consolidation chemotherapy for localized nasal natural killer/T-cell lymphoma.
Tsai HJ, Lin SF, Chen CC, Chen TY, et al · · 2015 · cited 25× · PMID 24957163 · DOI 10.1111/ejh.12405 -
The war between the immune system and the tumor - using immune biomarkers as tracers.
Yang K, Lu R, Mei J, Cao K, et al · · 2024 · cited 9× · PMID 38816871 · DOI 10.1186/s40364-024-00599-5
Verify or expand the search:
- PubMed search for NCT00292695
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other National Health Research Institutes, Taiwan trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00292695 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Health Research Institutes, Taiwan
- Last refreshed: 28 October 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00292695.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing