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NCT00292695

A Phase II Study of Concurrent Chemoradiation for The Localized Nasal NK/T-cell Lymphoma

Completed Phase 2 Last updated 28 October 2013
What this trial tests

Phase 2 trial testing VP-16, Cisplatin, Ifosfamide, Dexamethosone, Mesna, IF-RT in Lymphoma in 33 participants. Completed in 1 December 2010.

Timeline
1 May 2006
Primary endpoint
1 December 2009
1 December 2010

Quick facts

Lead sponsorNational Health Research Institutes, Taiwan
PhasePhase 2
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment33
Start date1 May 2006
Primary completion1 December 2009
Estimated completion1 December 2010
Sites1 location across Taiwan

Drugs / interventions tested

Conditions studied

Sponsor

National Health Research Institutes, Taiwan

Who can join

Under 70, any sex, with Lymphoma. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

To determine whether adding combinational chemotherapy concurrently to conventional radiation will improve the response rate, event-free survival, and overall survival. To test the dose intensity and toxicity of chemotherapy in concurrence with radiation. To detect the blood EBV DNA level in Chinese Nasal NK/T-cell lymphoma patients and correlate to the treatment response and prognosis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Long-term results of a phase II trial with frontline concurrent chemoradiotherapy followed by consolidation chemotherapy for localized nasal natural killer/T-cell lymphoma.
    Tsai HJ, Lin SF, Chen CC, Chen TY, et al · · 2015 · cited 25× · PMID 24957163 · DOI 10.1111/ejh.12405
  2. The war between the immune system and the tumor - using immune biomarkers as tracers.
    Yang K, Lu R, Mei J, Cao K, et al · · 2024 · cited 9× · PMID 38816871 · DOI 10.1186/s40364-024-00599-5

Verify or expand the search:

Other recruiting trials for Lymphoma

Currently open trials in the same condition.

Other National Health Research Institutes, Taiwan trials

Trials by the same sponsor.

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Data sources for this page

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