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Rifaximin in Standard Three-Day Dosing With and Without the Antimotility Drug, Loperamide, in the Treatment of Travelers' Diarrhea
Most cases of travelers' diarrhea are caused by bacterial pathogens which respond slowly to antibiotic treatment.The study was designed to determine the value of rapidly acting loperamide (imodium) combined with curative dose of the poorly absorbed rifaximin in travelers' diarreha treatment.
Details
| Lead sponsor | The University of Texas Health Science Center, Houston |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 316 |
| Start date | 2004-06 |
| Completion | 2005-08 |
Conditions
- Travelers' Diarrhea
Interventions
- Rifaximin and loperamide
Primary outcomes
- The major outcome parameter was time from initiation of therapy until passage of the last unformed stool before becoming well (TLUS).
Countries
Mexico