Different Treatment Regimens of Calcipotriol Cream and Combination (Calcipotriol/Betamethasone Dipropionate) Ointment in Psoriasis Vulgaris

NCT00216892 Phase 4 COMPLETED

Patients with psoriasis vulgaris of the trunk and/or limbs are randomised to treatment with: 1. 4 weeks of ointment containing calcipotriol and betamethasone dipropionate followed by 8 weeks of calcipotriol cream 2. 4 weeks of (calcipotriol plus betamethasone dipropionate) ointment followed by 8 weeks of calcipotriol cream on weekdays/ (calcipotriol plus betamethasone dipropionate) ointment on weekends 3. 4 weeks of (calcipotriol plus betamethasone dipropionate) ointment followed by 8 weeks of vehicle of calcipotriol cream The objective is to compare the efficacy and safety of the different treatment regimens

Details

Lead sponsor	LEO Pharma
Phase	Phase 4
Status	COMPLETED
Enrolment	1032
Start date	2005-04
Completion	2005-12

Conditions

• Psoriasis Vulgaris

Interventions

• Calcipotriol, (calcipotriol + betamethasone)

Primary outcomes

• Efficacy of regimen (a) versus regimen (c) by % change in PASI at week 12

Countries

Belgium, Canada, France, Germany, Netherlands, Spain, United Kingdom