Efficacy of AXERT (Almotriptan Malate) in the Acute Treatment of Migraine: A Pilot Study of the Potential Impact of Preventive Therapy With TOPAMAX (Topiramate)

NCT00210496 Phase 4 COMPLETED

The purpose of this study is to evaluate the impact of topiramate (migraine prevention medicine) on the effectiveness of almotriptan malate (acute migraine medicine) when treating acute migraine headaches.

Details

Lead sponsor	Janssen-Ortho LLC
Phase	Phase 4
Status	COMPLETED
Enrolment	406
Start date	2005-06
Completion	2007-06

Conditions

• Migraine
• Classic Migraine
• Common Migraine

Interventions

• topiramate; almotriptan malate

Primary outcomes

• The primary effectiveness parameter will be the proportion of subjects in each treatment group who achieve a Sustained Pain Free (SPF) response during the first qualifying headache of the Assessment Period.