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NCT00204230

Randomized Controlled Study: Effect of Mycophenolatmofetil in Patients With Histologically Proven Chronic Allograft Nephropathy

Terminated NA Last updated 12 September 2005
What this trial tests

NA trial testing mycophenolate mofetil (drug) in Immunosuppressive Agents in 86 participants. Terminated before completion.

Timeline
1 October 1999
1 September 2002

Quick facts

Lead sponsorUniversity Hospital Muenster
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment86
Start date1 October 1999
Estimated completion1 September 2002

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital Muenster

Who can join

Adults 18 to 70, any sex, with Immunosuppressive Agents or Kidney Failure, Chronic. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

Prospective, randomised study: Effect of mycophenolatmofetil (MMF) and CNI withdrawal in patients with histologically proven chronic allograft nephropathy Indication: change in immunosuppressive treatment of chronic allograft nephropathy (CAN)after renal transplantation Hypothesis: Antimetabolite MMF is able to stop progression of CAN and improve blood pressure/ metabolic parameters and structural vessel wall changes Primary Target:effects of CNI withdrawal and MMF on renal function: stabilisation and/or improvement Secondary Targets: Incidence of adverse events Evaluation of the calcineurin inhibitor free MMF treatment effects on blood pressure, lipids, glucose metabolism and on structural and functional vesselwallchanges Method:open prospective, randomized two-tailed, monocentric study

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Immunosuppressive Agents

Currently open trials in the same condition.

Other University Hospital Muenster trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00204230.

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