Pilot Study I for Treatment of Cancer in Children With Ataxia-Telangiectasia

NCT00187057 NA COMPLETED

This is a pilot/feasibility study designed to investigate the feasibility of treating children with Ataxia-Telangiectasia (A-T) and cancer with regimens nearly as intense as non-A-T patients with cancer would receive.

Details

Lead sponsor	St. Jude Children's Research Hospital
Phase	NA
Status	COMPLETED
Enrolment	6
Start date	2002-09
Completion	2013-06

Conditions

• Ataxia-Telangiectasia

Interventions

• vinblastine, vincristine, prednisone, daunorubicin
• doxorubicin, methotrexate, cyclophosphamide, L-asparaginase
• etoposide, cytarabine, mercaptopurine
• dexamethasone, procarbazine
• chemotherapy, intrathecal chemotherapy, steroid therapy

Primary outcomes

• To determine the feasibility of delivering modified intensive chemotherapy to children with A-T who present with cancer. — The completion of treatment

Countries

United States