Last reviewed · How we verify
Short Course of Quinine Plus a Single Dose of Sulphadoxine-Pyrimethamine for Plasmodium Falciparum Malaria
Quinine remains the treatment of choice of hospitalised malaria cases. The long treatment duration of 7 days, and adverse reactions often hamper its adequate use. Reducing the treatment duration by adding sulfadoxine-pyrimethamine may enhance compliance and reduce side effects. The efficacy of a 3-day treatment of quinine plus sulfadoxine-pyrimethamine for the treatment of hospitalised, uncomplicated malaria cases was assessed.
Details
| Lead sponsor | Albert Schweitzer Hospital |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 50 |
| Start date | 2003-04 |
| Completion | 2004-02 |
Conditions
- Malaria
Interventions
- Quinine plus sulfadoxine-pyrimethamine
Primary outcomes
- Proportion of cured patients by day 28
Countries
Gabon