Randomized Clinical Trial Comparing the Efficacy of Percutaneous Closure of Patent Foramen Ovale (PFO) With Medical Treatment in Patients With Cryptogenic Embolism

NCT00166257 Phase 4 UNKNOWN

The purpose of this study is to compare two treatments strategies to prevent further attacks in patients who have suffered an stroke or occlusion of a major artery with no obvious reason other than a persistent small opening between the upper heart chambers

Details

Lead sponsor	Foundation for Cardiovascular Research, Zurich
Phase	Phase 4
Status	UNKNOWN
Enrolment	414
Start date	2000-02
Completion	2011-05

Conditions

• Embolism, Paradoxical
• Heart Septal Defects, Atrial

Interventions

• Percutaneous closure of patent foramen ovale
• Medical antitrhombotic treatment

Primary outcomes

• Time to death (Fatal stroke, cardiovascular, non-CV), — continuosly
• non-fatal cerebrovascular event, — continuosly
• peripheral embolism — continuosly

Countries

Australia, Austria, Belgium, Switzerland