LAAM With Behavioral Treatment for Opioid/Cocaine Abuse

NCT00158288 Phase 2 COMPLETED

Although LAAM, a derivative of methadone, has been successfully used as an alternative to methadone maintenance in opioid addicts, its effect on concurrent opioid and cocaine abuse has not been ascertained. Thus, this study proposes to examine the clinical efficacy of low- and high-dose LAAM maintenance on opioid and cocaine use in opioid-dependent cocaine abusers. In addition, since contingency management procedures have demonstrated some success in decreasing cocaine use in cocaine-abusing individuals, this study also proposes to examine the clinical efficacy of the presence or absence of contingency management procedures targeting illicit drug use.

Details

Lead sponsor	National Institute on Drug Abuse (NIDA)
Phase	Phase 2
Status	COMPLETED
Enrolment	140
Start date	1997-03
Completion	2001-08

Conditions

• Behavior Therapy
• Cocaine
• Contingency Management
• Heroin Dependence
• LAAM
• Opioid Dependence
• Substance-Related Disorders
• Alcohol & Drug Use

Interventions

• LAAM

Primary outcomes

• Urine toxicology for cocaine

Countries

United States