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NCT00149201
Randomized Phase III Study of 5-FU Continuous Infusion (5FUci) Versus MTX+5-FU Sequential Therapy (MF) in Gastric Cancer With Peritoneal Metastasis (JCOG0106-MF, MF/5FU)
Phase 3 trial testing 5-FU continuous infusion in Gastric Cancer in 160 participants. Completed in 1 April 2008.
1 April 2008
Quick facts
| Lead sponsor | Japan Clinical Oncology Group |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 160 |
| Start date | 1 November 2002 |
| Primary completion | 1 April 2008 |
| Estimated completion | 1 April 2008 |
| Sites | 34 locations across Japan |
Drugs / interventions tested
- 5-FU continuous infusion — full drug profile →
- MTX + 5-FU sequential therapy — full drug profile →
Conditions studied
- Gastric Cancer — all drugs for Gastric Cancer →
- Neoplasm Metastasis — all drugs for Neoplasm Metastasis →
Sponsor
Japan Clinical Oncology Group
Who can join
Adults 20 to 75, any sex, with Gastric Cancer or Neoplasm Metastasis. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
- overall survival
Sponsor's own description
To develop effective chemotherapy regimen against gastric cancer with peritoneal metastasis
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Chemotherapy for advanced gastric cancer.
Wagner AD, Syn NL, Moehler M, Grothe W, et al · · 2017 · cited 532× · PMID 28850174 · DOI 10.1002/14651858.cd004064.pub4 -
First-line systemic therapy for advanced gastric cancer: a systematic review and network meta-analysis.
Cheng J, Cai M, Shuai X, Gao J, et al · · 2019 · cited 22× · PMID 31632469 · DOI 10.1177/1758835919877726
Verify or expand the search:
- PubMed search for NCT00149201
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Gastric Cancer
Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00149201 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Japan Clinical Oncology Group
- Last refreshed: 2 February 2009
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00149201.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing