The Effect of Folic Acid Supplementation on Efficacy of Sulfadoxine-pyrimethamine in Pregnant Women in Western Kenya

NCT00130065 Phase 4 COMPLETED

The purpose of this study is to determine whether folic acid, which is often routinely given to pregnant women to prevent birth defects and anemia, affects the efficacy of sulfadoxine-pyrimethamine, another drug that is routinely given to pregnant women in highly malarious areas, for prevention of the adverse effects of malaria during pregnancy.

Details

Lead sponsor	Centers for Disease Control and Prevention
Phase	Phase 4
Status	COMPLETED
Enrolment	600
Start date	2003-11
Completion	2006-02

Conditions

• Malaria

Interventions

• Sulfadoxine-pyrimethamine/folic acid
• Sulfadoxine-pyrimethamine/placebo

Primary outcomes

• Peripheral parasitemia
• Hemoglobin level

Countries

Kenya