Who is sponsoring NIA-Plaque?

NIA-Plaque is sponsored by Johns Hopkins University.

What condition does NIA-Plaque study?

NIA-Plaque studies Atherosclerosis, Cardiovascular Disease.

What drugs are being tested in NIA-Plaque?

Interventions: any statin, niacin, Placebo.

What is the status of NIA-Plaque?

NIA-Plaque is currently COMPLETED.

Last reviewed 2017-10-04 · How we verify

HDL Increased Plaque Stabilization in the Elderly (NIA-Plaque)

NCT00127218 Phase 3 COMPLETED Results posted

The purpose of this study is to investigate the added benefits of increased high-density lipoprotein (HDL) cholesterol serum levels over and above those achieved by lipid lowering therapy guided by current guidelines, in older individuals with cardiovascular disease.

Details

Lead sponsor	Johns Hopkins University
Phase	Phase 3
Status	COMPLETED
Enrolment	145
Start date	2003-09
Completion	2008-12

Conditions

Atherosclerosis
Cardiovascular Disease

Interventions

any statin
niacin
Placebo

Primary outcomes

Changes in Plaque Architecture and Composition Directly Measured by Magnetic Resonance Imaging (MRI) in the Aorta and Carotid Arteries — 18 months
The primary endpoint is Changes in plaque architecture and composition directly measured by magnetic resonance imaging (MRI) in the aorta and carotid arteries.

Countries

United States