NCT00074906 is a Phase 3 clinical trial of Venticute in Pneumonia, sponsored by Takeda.

Who is sponsoring NCT00074906?

NCT00074906 is sponsored by Takeda.

What drugs are being tested in NCT00074906?

Interventions in NCT00074906: Venticute.

Is NCT00074906 still recruiting?

NCT00074906 is currently completed. Last updated 4 May 2012.

Last reviewed 2012-05-04 · How we verify

NCT00074906

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Venticute in Patients With Pneumonia or Aspiration of Gastric Contents Leading to Intubation, Ventilation, and Severe Oxygenation Impairment: A Randomized, Multinational, Multicenter, Parallel Group, Double Blind, Control Group Study

Completed Phase 3 Last updated 4 May 2012

What this trial tests

Phase 3 trial testing Venticute in Pneumonia in 1,200 participants. Completed in 1 June 2008.

Timeline

1 November 2003

Primary endpoint
1 March 2008

1 June 2008

Quick facts

Lead sponsor	Takeda
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	1,200
Start date	1 November 2003
Primary completion	1 March 2008
Estimated completion	1 June 2008
Sites	92 locations across Australia, Austria, Belgium, Denmark, Estonia, Finland, Germany, Greece

Drugs / interventions tested

Venticute — full drug profile →

Conditions studied

Pneumonia — all drugs for Pneumonia →

Sponsor

Takeda — full company profile →

Who can join

Adults 12 to 85, any sex, with Pneumonia. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Survival on day 28
Time frame: 28 days

Sponsor's own description

Study to demonstrate that administration of Venticute increases survival of patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygenation impairment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Biomimicry of surfactant protein C.
Brown NJ, Johansson J, Barron AE. · · 2008 · cited 20× · PMID 18834153 · DOI 10.1021/ar800058t

Verify or expand the search:

Other recruiting trials for Pneumonia

Currently open trials in the same condition.

NCT07453966 — Efficacy and Safety of Intrapulmonary Percussive Ventilation in Patients With Pulmonary Infection Receiving Invasive Mec · NA · recruiting
NCT07251465 — A Study to Learn How Effective is PCV20 to Help Stop Adults Who Have a Higher Chance of Getting Pneumonia · active not recruiting
NCT07311343 — Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia · Phase 4 · recruiting
NCT07298889 — High PEEP in Noninvasive Ventilation Patients With Pneumonia or ARDS · NA · recruiting
NCT06911658 — Infectious Complications After Esophagectomy · recruiting

Other Takeda trials

Trials by the same sponsor.

NCT05669729 — A Survey to Assess Participants', Caregivers', and Nurses' Use and Understanding of Educational Material on Velagluceras · not yet recruiting
NCT07403968 — A Study of Zasocitinib (TAK-279) in Adults With Active Crohn's Disease · Phase 2 · not yet recruiting
NCT07293364 — A Study to Learn About the C1-Inhibitor Function as Diagnosis for Hereditary Angioedema · NA · not yet recruiting
NCT07218393 — A Study About the Diagnosis and Management of Hereditary Angioedema (HAE) in Egypt · not yet recruiting
NCT07445087 — A Study of Takhzyro in Teenagers and Adults With Hereditary Angioedema (HAE) in South Korea · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00074906 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Takeda
Last refreshed: 4 May 2012

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00074906.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing