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NCT00067223
Studying Use-Dependent Plasticity
trial in Healthy in 28 participants. Completed in 25 June 2007.
Quick facts
| Lead sponsor | National Institute of Neurological Disorders and Stroke (NINDS) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 28 |
| Start date | 5 August 2003 |
| Estimated completion | 25 June 2007 |
| Sites | 1 location across United States |
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Who can join
18 and older, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recent studies suggest that when patients learn a new motor movement, it may cause a change in the way the nerves act in the area of the brain that controls that movement. This change is called use-dependent plasticity. The purpose of this study is to determine the direction and extent of the changes that take place in the brain areas that control movement in the untrained finger after the training of the opposite finger. The study outcomes may help researchers to develop rehabilitation strategies for people who have suffered brain injuries. Eighteen healthy adults age 18 years or older will be enrolled in this study. Participants will undergo a clinical exam and then come back to the Clinical Center three times for sessions that will last approximately 2 hours each. For each session, participants' forearms will be immobilized and a small electronic device will be attached to each index finger so that researchers can measure their movements. Participants will be asked to move either index finger and to observe and concentrate on its movement. Investigators will perform transcranial magnetic stimulation (TMS) before and after these motor exercises. For TMS, a wire coil is held over the scalp and a brief electrical current passes through the coil, creating a magnetic pulse that electrically stimulates the brain.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00067223
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
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Other National Institute of Neurological Disorders and Stroke (NINDS) trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00067223 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Neurological Disorders and Stroke (NINDS)
- Last refreshed: 2 July 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00067223.
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