Randomized Phase III Trial Comparing Targretin Capsules/Carboplatin/Paclitaxel Versus Carboplatin/Paclitaxel in Chemotherapy-Naïve Patients With Advanced or Metastatic Non-Small Cell Lung Cancer

NCT00050960 Phase 3 COMPLETED Results posted

This study evaluates the use of Targretin capsules (bexarotene) in combination with standard chemotherapy for the treatment of metastatic Non-Small Cell Lung Cancer (NSCLC) in patients who have not yet received chemotherapy for their lung cancer.

Details

Lead sponsor	Eisai Inc.
Phase	Phase 3
Status	COMPLETED
Enrolment	612
Start date	2002-05
Completion	2005-03

Conditions

• Non-small Cell Lung Cancer

Interventions

• bexarotene with carboplatin and paclitaxel
• carboplatin and paclitaxel

Primary outcomes

• Overall Survival — From date of randomization to date of death

Countries

United States, Austria, Canada, France, Germany, Spain