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Optimization of Electroconvulsive Therapy
This study will evaluate the effectiveness of electroconvulsive therapy (ECT) administered with medication for the treatment of a major depressive episode (unipolar or bipolar) and will compare two types of ECT.
Details
| Lead sponsor | New York State Psychiatric Institute |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 340 |
| Start date | 2001-02 |
| Completion | 2006-12 |
Conditions
- Depression
- Depressive Disorder
- Bipolar Disorder
Interventions
- High dosage electroconvulsive therapy
- Nortriptyline
- Venlafaxine
- Lithium
- Low dosage electroconvulsive therapy
Primary outcomes
- Neurocognitive battery — Measured at baseline and at 2 and 6 months after the acute ECT course
- Clinical evaluations, side effect evaluations, and blood level determinations — Measured weekly for the first month, every 2 weeks until Week 12, and every 4 weeks for the remaining 12 weeks
Countries
United States