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A Phase II Trial of Patients With Limited Stage Small Cell Lung Cancer Treated With Thoracic Radiation Therapy and Chemotherapy With Cisplatin/Etoposide Followed by Cisplatin/Etoposide and Anti-Idiotype Monoclonal Antibody Vaccines
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high energy x-rays to damage tumor cells. Vaccines may make the body build an immune response to kill tumor cells. Combining chemotherapy and radiation therapy with vaccine therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining chemotherapy and radiation therapy with vaccine therapy in treating patients who have limited-stage small cell lung cancer.
Details
| Lead sponsor | SWOG Cancer Research Network |
|---|---|
| Phase | Phase 2 |
| Status | TERMINATED |
| Enrolment | 9 |
| Start date | 2003-01 |
| Completion | 2003-05 |
Conditions
- Lung Cancer
Interventions
- monoclonal antibody 11D10 anti-idiotype vaccine
- monoclonal antibody GD2 anti-idiotype vaccine
- cisplatin
- etoposide
- radiation therapy
Primary outcomes
- overall survival — up to 5 years
time from date of registration to date of death
Countries
United States, Canada