NCT00031408 is a clinical trial in HIV Infections, sponsored by Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections.

What condition does NCT00031408 study?

NCT00031408 studies HIV Infections.

Is NCT00031408 still recruiting?

NCT00031408 is currently active, enrolled. Last updated 7 October 2025.

Last reviewed 2025-10-07 · How we verify

NCT00031408

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Consent for Use of Stored Patient Specimens for Future Testing

Active, enrolled Last updated 7 October 2025

What this trial tests

trial in HIV Infections in 17,444 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

13 February 2002

Primary endpoint
31 December 2027

31 December 2027

Quick facts

Lead sponsor	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Status	Active, enrolled
Study type	OBSERVATIONAL
Enrollment	17,444
Start date	13 February 2002
Primary completion	31 December 2027
Estimated completion	31 December 2027
Sites	63 locations across Puerto Rico, United States

Conditions studied

HIV Infections — all drugs for HIV Infections →

Sponsor

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Who can join

Eligibility, any sex, with HIV Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

HIV escape mutations occur preferentially at HLA-binding sites of CD8 T-cell epitopes.
Bronke C, Almeida CM, McKinnon E, Roberts SG, et al · · 2013 · cited 36× · PMID 23276808 · DOI 10.1097/qad.0b013e32835e1616
Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes.
Almeida CA, Bronke C, Roberts SG, McKinnon E, et al · · 2011 · cited 27× · PMID 21821798 · DOI 10.4049/jimmunol.1100691

Verify or expand the search:

Other recruiting trials for HIV Infections

Currently open trials in the same condition.

NCT07225530 — Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR) · NA · recruiting
NCT07202546 — A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · recruiting
NCT06694753 — Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall · Phase 1 · recruiting
NCT07235852 — Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention · NA · recruiting
NCT06665646 — Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Ad · Phase 1 · recruiting

Other Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections trials

Trials by the same sponsor.

NCT06205589 — Therapeutic ID93 + GLA-SE Vaccination in Participants With Rifampicin-Susceptible Pulmonary TB · Phase 2 · not yet recruiting
NCT06856174 — Menopausal HT for Women Living With HIV (HoT) · Phase 4 · not yet recruiting
NCT06205602 — Antiretrovirals Combined With Antibodies for HIV-1 Cure In Africa · Phase 2 · recruiting
NCT06031272 — Pausing Antiretroviral Treatment Under Structured Evaluation · Phase 1 · active not recruiting
NCT05985642 — Observational PIC Destination Cohort · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00031408 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Last refreshed: 7 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00031408.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing