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NCT00023049
Genetic Analysis of Hereditary Disorders of Hearing and Balance
trial in Sensorineural Hearing Loss in 335 participants. Completed.
Quick facts
| Lead sponsor | National Institute on Deafness and Other Communication Disorders (NIDCD) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 335 |
| Start date | 23 December 2002 |
| Sites | 2 locations across United States, Nigeria |
Conditions studied
- Sensorineural Hearing Loss — all drugs for Sensorineural Hearing Loss →
- Hearing Disorder — all drugs for Hearing Disorder →
- Vestibular Disease — all drugs for Vestibular Disease →
Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Who can join
Under 99, any sex, with Sensorineural Hearing Loss or Hearing Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will try to identify the genetic causes of hereditary hearing loss or balance disorders. People with a hearing or balance disorder that affects more than one family member may be eligible for this study. They and their immediate family members may undergo some or all of the following procedures: * Medical and family history, including questions about hearing, balance and other ear-related issues, and review of medical records. * Routine physical examination. * Blood draw or buccal swab (brushing inside the cheek to collect cells) - Tissue is collected for DNA analysis to look for changes in genes that may be related to hearing loss. * Hearing tests - The subject listens for tones emitted through a small earphone. * Balance tests to see if balance functions of the inner ear are associated with the hearing loss In one test the subject wears goggles and watches moving lights while cold or warm air is blown into the ears. A second test involves sitting in a spinning chair in a quiet, dark room. * Photograph - A photograph may be taken as a record of eye shape and color, distance between the eyes, and hair color. * Computed tomography (CT) and magnetic resonance imaging (MRI) scans - These tests show the structure of the inner ear. For CT, the subject lies still for a short time while X-ray images are obtained. For MRI, the patient lies on a stretcher that is moved into a cylindrical machine with a strong magnetic field. The magnetic field and radio waves produce images of the inner ear. The radio waves cause loud thumping noises that can be muffled by the use of earplugs.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00023049
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sensorineural Hearing Loss
Currently open trials in the same condition.
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- NCT06495268 — Healthy heaAring for Healthy Ageing: Data-driven Hearing Rehabilitation Intervention to Promote Healthy Hearing · NA · active not recruiting
- NCT06226558 — Long-Term Outcomes of Children With Congenital CMV in New York State · recruiting
Other National Institute on Deafness and Other Communication Disorders (NIDCD) trials
Trials by the same sponsor.
- NCT07149428 — Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional · not yet recruiting
- NCT06461949 — Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusiti · Phase 3 · withdrawn
- NCT04915183 — Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer · Phase 2 · recruiting
- NCT06303180 — NIDCD Otolaryngology Clinical Protocol Biospecimen Bank · recruiting
- NCT05670496 — Collection of Clinical Data and Specimens for Research in Hearing, Balance, Taste, Smell, Voice, Speech, and Language Di · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00023049 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute on Deafness and Other Communication Disorders (NIDCD)
- Last refreshed: 25 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00023049.
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